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Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation

ChEBI2013-11-17 更新2026-07-21 收录

生发中心B细胞

转录协同抑制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-47784 数据链接链接失效反馈

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资源简介：

Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation

应用场景：

创建时间：

2013-11-17

细胞基因表达

生发中心B细胞

Microarrays of gene expression in mouse germinal center B cells photoactivated in the light zone or dark zone, and of naïve cells for comparison. We used microarray data to identify genes differential

NIAID Data Ecosystem70

Expression data from murine wildtype and Sh3gl1-/- B cells. Expression data from murine wildtype and Sh3gl1-/- B cells

生发中心B细胞

内吞调控与免疫代谢

We show that antigen internalization depends both on constitutive, clathrin-mediated endocytosis and on antigen-induced, clathrin-independent endocytosis mediated by endophilin A2. Although endophilin

NIAID Data Ecosystem50

Gene expression in germinal center light zone, dark zone, and naïve B cells. Mus musculus

生发中心B细胞

细胞基因表达

NIAID Data Ecosystem20

RNAseq of germinal center B cells from Blimp-1-GFP reporter mice with an ablatable TfH compartment.

生发中心B细胞

Tfh细胞免疫调控

RNAseq of germinal center B cells (B220+IgDlowCD95+GL7+) with different Blimp-1-GFP reporter level in the presence of TfH cells or 72 hr after their depletion. Sorted germinal center populations were

NIAID Data Ecosystem50

Tracking immunoglobulin gene editing and transcriptomic changes in GC B cells by single-cell analysis

生发中心B细胞

免疫球蛋白基因编辑

In response to T cell-dependent antigens, mature B cells are stimulated to form germinal centers, which are the place of B cell affinity maturation and selection. Here, we dissected the heterogeneity

NIAID Data Ecosystem30

Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation

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