REPIC
收藏资源简介:
The REPIC (RNA EPItranscriptome Collection) database records about 10 million peaks called from publicly available m6A-seq and MeRIP-seq data . These data were collected from 672 samples of 49 studies, covering 61 cell lines or tissues in 11 organisms. REPIC allows users to query N6-methyladenosine (m6A) modification sites by specific cell lines or tissue types. In addition, it integrates m6A/MeRIP-seq data with 1418 histone ChIP-seq and 118 DNase-seq data tracks from the ENCODE project in a modern genome browser to present a comprehensive atlas of m6A methylation sites, histone modification sites, and chromatin accessibility regions.
REPIC(RNA表观转录组数据库,RNA EPItranscriptome Collection)数据库收录了约1000万个从公开可用的m6A测序(m6A-seq)与甲基化RNA免疫沉淀测序(MeRIP-seq)数据中鉴定得到的修饰富集峰。该数据集来自49项研究的672个样本,覆盖11个物种的61种细胞系或组织。REPIC支持用户通过指定细胞系或组织类型查询N6-甲基腺嘌呤(m6A)修饰位点。此外,该数据库将m6A/MeRIP-seq数据与ENCODE项目的1418条组蛋白染色质免疫沉淀测序(ChIP-seq)数据轨道及118条DNase测序(DNase-seq)数据轨道整合至现代化基因组浏览器中,以全面展示m6A甲基化位点、组蛋白修饰位点与染色质开放区域的综合调控图谱。




