Canine fecal microbiome: Idiopathic epilepsy

We aimed to identify differences in fecal metabolome and microbiome between healthy and dogs with IE. To this purpose, fecal samples of healthy (n = 39) and dogs with IE (n = 49) were metabolically profiled (n = 148 metabolites) and fingerprinted (n = 3690 features) using liquid chromatography coupled to mass spectrometry, and the bacterial phylogeny examined using 16S rRNA sequencing. Dogs with IE were categorized as drug-resistant (DR) (n = 27) or mild phenotype (MP) (n = 22).