RNA sequencing data describing transcriptional changes in aorta of ApoE-/- mice after alpha 7 nicotinic acetylcholine receptor (a7nAChR) stimulation.

This manuscript is a companion paper to Ulleryd M.U. et al (1). Data shown here include RNA sequencing data from whole aorta of ApoE-/- mice treated with the alpha 7 nicotinic acetylcholine receptor (a7nAChR) agonist AZ6983 for 8 weeks using subcutaneously implanted osmotic minipumps. 1. Ulleryd MA, Mjornstedt F, Panagaki D, Yang LJ, Engevall K, Gutierrez S, et al. Stimulation of alpha 7 nicotinic acetylcholine receptor (a7nAChR) inhibits atherosclerosis via immunomodulatory effects on myeloid cells Re-submitted. 2019. Overall design: ApoE-/- mice were treated with alpha 7 nicotinic acetylcholine receptor (a7nAChR) agonist AZ6983 or vehicle for 8 weeks using subcutaneously implanted osmotic minipumps. RNA from whole aorta were extracted and used for RNA sequencing analysis. n=6 per group.