Low H3K27me3 define poorly prognostic pediatric posterior fossa ependymomas
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https://www.ncbi.nlm.nih.gov/sra/SRP092467
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资源简介：
A subgroup of Posterior fossa ependymomas show reduced H3K27me3 are more invasive, exhibit poor prognosis and epigenetically deregulated genes converge on radial glial factors, suggesting developing cerebellar radial glia as candidate cells-of-origin. Overall design: H3K27me3 ChIP sequencing was performed on 3 posterior fossa (PF) and 3 supratentorial (ST) ependymoma samples. 3 PF ependmoma samples showed low H3K27me3 and designated PF_H3K27me3-ve; all 3 ST ependymoma samples show high H3K27me3 and desginated ST_H3K27me3+ve
创建时间：
2021-07-15
