PTF1A related regulatory pathway

By summarizing published data together with our own results, this pathway shows a complicated relationships between transcriptional factors, miRNAs and some functional genes which are correlated together to generate a whole sight in early mouse development centered around Ptf1a, although there are some hypothetical relationships and the distinct development of dorsal and ventral pancreas in very early stage is neglected.

通过综合汇总已发表的资料及我们的研究成果，本路径图揭示了转录因子、miRNA与某些功能基因之间复杂的相互作用关系，这些基因相互关联，共同构成了围绕Ptf1a的早期小鼠发育的全景图。尽管存在一些假设性的关系，但在非常早期阶段，背胰腺和腹胰腺的独立发育被忽略。