Crystal Structure of small molecule acrylamide 11 covalently bound to K-Ras G12C
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Crystal Structure of small molecule acrylamide 11 covalently bound to K-Ras G12C Descriptor: 1-(4-{[(4,5-dichloro-2-methoxyphenyl)amino]acetyl}piperazin-1-yl)propan-1-one, GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase Authors: Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. Deposit date: 2013-08-05 Release date: 2013-11-27 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.94 Å) Cite: K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature, 503, 2013
创建时间：
2013-08-05
