five

Ctenopharyngodon idella, CIK cells, pull-down MS

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NIAID Data Ecosystem2026-05-01 收录
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https://www.omicsdi.org/dataset/pride/PXD036006
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IL6-STAT3 is a canonical pro-inflammatory pathway that is highly related to temperature fluctuation and viral infection. Our understanding concerning how the crosstalk between IL6-STAT3 signaling axis and environmental temperature determines viral infection remains rudimentary. Employing an aquatic reovirus infection in ectotherms as a model system, we delineated a pivotal role of IL6-STAT3-HSP90 signaling axis in temperature dependent pathogenesis through interacting with viral capsid proteins to promote viral entry.
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2023-05-09
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