Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor
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Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor Descriptor: (4-CHLOROPHENYL)[3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ACETIC ACID, Ubiquitin-protein ligase E3 Mdm2 Authors: Grasberger, B.L, Schubert, C, Koblish, H.K, Carver, T.E, Franks, C.F, Zhao, S.Y, Lu, T, LaFrance, L.V, Parks, D.J. Deposit date: 2004-04-29 Release date: 2005-02-08 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells J.Med.Chem., 48, 2005
创建时间：
2004-04-29
