silencing of endogenous Dnmt3L in Tg-Miwi2P-asDnmt3L mice_E16-piRNA
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https://www.ncbi.nlm.nih.gov/sra/DRP009333
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We produced the transgenic mice expressing antisense-Dnmt3L under the Miwi2 promoter (Tg-Miwi2P-asDnmt3L).Tg-Miwi2P-asDnmt3L mice showed reduced endogenous Dnmt3L RNA expression and a phenotype quite similar to that of DNMT3L-difficient mice. We examined the piRNA expression in E16.5 testis of each Tg-Miwi2P-asDnmt3L (Tg-E, Tg-B, Tg-BE) and control mice.
创建时间:
2022-12-17



