Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

ChEBI2009-12-10 更新2026-07-21 收录

神经髓鞘形成调控

Wnt信号通路神经病理

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-19403 数据链接链接失效反馈

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资源简介：

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

创建时间：

2009-12-10

Chromatin Remodeler CHD7 mutated in CHARGE Syndrome Interacts with Sox10 to Regulate Timing of CNS Myelination and Remyelination [ChIP-seq]. Rattus norvegicus

神经髓鞘形成调控

染色质重塑与转录调控

Mutations in CHD7, encoding ATP-dependent chromodomain-helicase-DNA-binding protein 7, in CHARGE syndrome leads to multiple congenital anomalies including growth retardation, craniofacial malformation

NIAID Data Ecosystem30

Transient gene melting governs the timing of oligodendrocyte maturation [miRNA-seq]. Transient gene melting governs the timing of oligodendrocyte maturation [miRNA-seq]

少突胶质细胞成熟

神经髓鞘形成调控

Cellular maturation is a crucial step for tissue formation and function, distinct from the initial steps of differentiation and cell fate specification. In the central nervous system, failure of oligo

NIAID Data Ecosystem20

Chromatin Remodeler CHD7 mutated in CHARGE Syndrome Interacts with Sox10 to Regulate Timing of CNS Myelination and Remyelination [RNA-seq]

神经髓鞘形成调控

染色质重塑与神经发育

Chromatin Remodeler CHD7 mutated in CHARGE Syndrome Interacts with Sox10 to Regulate Timing of CNS Myelination and Remyelination [RNA-seq]

ChEBI2016-02-29 更新00

Identification of genome-wide targets of Olig2 in the adult mouse spinal cord using ChIP-Seq

转录因子靶点

神经髓鞘形成调控

Olig2 is a crucial factor in the specification and differentiation of oligodendrocyte precursor cells that give rise to mature, myelin-producing OLs in the developing and postnatal CNS; however, its r

NIAID Data Ecosystem20

STAG2 promotes the myelination transcriptional program in oligodendrocytes [scRNA-seq]. STAG2 promotes the myelination transcriptional program in oligodendrocytes [scRNA-seq]

神经髓鞘形成调控

单细胞转录组学

Cohesin folds chromosomes via DNA loop extrusion. Cohesin-mediated chromosome loops regulate transcription by shaping long-range enhancer-promoter interactions, among other mechanisms. Mutations of co

NIAID Data Ecosystem10

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

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