Sequencing of patient-derived organoids (PDOs) for primary and metastatic uveal melanoma was done to characterize PDOs as a novel platform for preclinical therapeutics studies.
TCGA Uveal Melanoma. Source data from GDAC Firehose. Previously known as TCGA Provisional. This dataset contains summary data visualizations and clinical data from a broad sampling of 80 carcinomas fr
Hotspot mutations in the spliceosome gene SF3B1 are reported in 20% of uveal melanomas. SF3B1 is involved in 3'-splice site (3'ss) recognition during RNA splicing; however, the molecular mechanisms of
Sequencing of patient-derived organoids (PDOs) for primary and metastatic uveal melanoma was done to characterize PDOs as a novel platform for preclinical therapeutics studies.