A widespread alternate form of cap-dependent mRNA translation initiation
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE115142
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资源简介：
We report the application of polysome profiling sequencing technology for high-throughput transcriptomics and translatomics in mammalian cells. We compare reduction of Dap5 to control in metastatic breast cancer cells in transcription and polysome enriched translation using RNA sequencing. Genome-wide transcriptomic and translatomic analyses indicate that DAP5 is required for translation of many transcription factor and receptor capped mRNAs and their mRNA targets involved in cell survival, motility, DNA repair and translation initiation, among other mRNAs. Examination of transcriptomics and translatomics in breast cancer cells.
创建时间：
2019-03-27
