Risk factors associated with sorafenib-induced toxicity, defined as any toxicity ≥grade 3 or hand foot skin reaction, hypertension and diarrhea grade ≥2.
收藏Figshare2015-12-02 更新2026-04-29 收录
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AUC, area under the curve; BMI, body mass index; ECOG PS, Eastern Cooperative Oncology Group Performance Status; m, mutant allele; NS, not significant; NT, not tested; OR, Odds ratio; Wt, wild-type allele.Quantitative results are expressed as median [interquartile range]*Heterozygotous patients (wt/m) for UGT1A9–2152 C>T and UGT1A9–275 T>A were the same; therefore the polymorphism for UGT1A9–275 T>A was not tested in the multivariate analysis
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2015-12-02
