Age-dependent Response of Isolated Male Germ Cells to Oxidative Stress

Alliance of Genome Resources2026-08-01 收录

细胞氧化应激

生殖衰老

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https://www.ncbi.nlm.nih.gov/gds/?term=GSE66976 数据链接链接失效反馈

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Study of the response of isolated male germ cells from young and aged Brown Norway Rats to oxidative stress.

Occurrence from Is degree of sociality associated with reproductive senescence? A comparative analysis across birds and mammals

生殖衰老

生物学

Comparison of the results found on reproductive senescence using our standardized procedure against the results found in the original studies

DataCite Commons2021-02-05 更新60

H 2 DCFDA positive cells quantification.

细胞氧化应激

ROS荧光定量

Each condition represents %H2DCFDA-positive germ cells (∼400 cells/group). Results are presented as means±S.D. of one representative experiment out of 4. *P<0.05 vs Basal.

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TGF-ß Sma/Mab Signaling Mutations Uncouple Reproductive Aging from Somatic Aging

生殖衰老

TGF-ß信号通路

Female reproductive cessation is one of the earliest age-related declines humans experience, occurring in mid-adulthood. Similarly, Caenorhabditis elegans' reproductive span is short relative to its t

NIAID Data Ecosystem10

Loss of the glucocorticoid receptor causes accelerated reproductive aging in female zebrafish

生殖衰老

斑马鱼基因敲除模型

Reproductive decline in mid-adult females isstablished phenotype of the aging process. Stress and the rise in glucocorticoids (GCs) accelerate reproductive aging, but little is known about the mechani

NIAID Data Ecosystem30

Global gene expression profiling and senescence biomarker analysis of hESC exposed to H2O2 induced non-cytotoxic oxidative stress

细胞氧化应激

衰老生物标志物

Human embryonic stem cells (hESCs) potentially offer new routes to study, on the basis of the Developmental Origins of Health and Disease (DOHaD) concept, how the maternal environment during pregnancy

NIAID Data Ecosystem20

Age-dependent Response of Isolated Male Germ Cells to Oxidative Stress

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