Base case lifetime costs, health benefits (per 100,000), and incremental costs effectiveness ratio of combined screening and treatment strategies for a cohort of individuals who are currently 50 years of age.

*Population weighted average (white male 44%, white female 45%, black male 5%, black female 6%) for fibrosis distribution: F0 13%, F1 51%, F2 13%, F3 10%, and F4 13%. All incremental cost and QALY are compared to the reference.
ICER = incremental cost-effectiveness ratio; IL-28B = interleukin-28B; QALY = quality-adjusted life-year.
“Dominated” indicates that the strategy costs more and provides fewer benefits than another strategy or a combination of two strategies.