Gene expression analysis of human fetal pancreatic niche cell lines: Wk17.5h and Wk20.1

We derived cell lines from the human pancreatic niche from different sites during different temporal stages of fetal development when beta cells are differentiating and maturing. This screen uncovered differences between the human pancreatic niche at fetal week 17.5 head of pancreas(Wk17.5h) and 20.1 doudeum (Wk 20.1) and control cell line human dermal fibroblast(HDF), illustrating a temporally changing, developmentally significant microenvironment. We characterized gene expression of human fetal-derived pancreatic mesenchymal and endothelial cell lines Wk 17.5h and Wk 20.1, with control cell line HDFs