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Supplementary Fig. 5a | FUS localization in ALS motor neurons (c-terminal antibody)

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NIAID Data Ecosystem2026-05-02 收录
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https://figshare.com/articles/dataset/Supplementary_Fig_5a_FUS_localization_in_ALS_motor_neurons_c-terminal_antibody_/22555123
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This item is part of the Figshare Project: Early mitochondrial dysfunction revealed across FUS- and TARDBP-ALS at single cell resolution From Data Availability Statement for the forthcoming paper in Nature Communications entitled: Single-cell RNA sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS "We have deposited all raw and processed RNA sequencing data generated in this study on the NCBI Gene Expression Omnibus (GEO) under the accession number GSE226482. The C9orf72-ALS bulk RNA sequencing data was retrieved directly from the authors of the study. [Items under this Figshare Project contain:] "Scans of fluorescent western blots, raw imaging files from confocal microscopy, the analysis files from Opera Phenix, qPCR data sets, and Seahorse assay result files." -------------------------------------------- [Item specific description:] FUS localization in PSC-derived motor neurons with ALS mutations. These files are confocal images analyzing FUS localisation in iPSC-derived ALS motor neurons. The file format is .czi, through the ZEN software (Zeiss). Zeiss recommends using ImageJ and the ImageJ-based Fiji software package. Information about the microscopy file format CZI can be found here: https://www.zeiss.com/microscopy/en/products/software/zeiss-zen/czi-image-file-format.html
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2025-04-24
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