Metadata record for the manuscript: The human intermediate prolactin receptor is a mammary proto-oncogene

Summary

This
metadata record provides details of the data supporting the claims of the
related manuscript: “The human intermediate prolactin
receptor is a mammary proto-oncogene”.

The
related study aimed to determine if a transforming event similar to that of truncated
mouse hormone prolactin receptor (hPRLr) occurs with the hPRLr in human breast
epithelial cells and to better understand the mechanism behind such
transformation.

Subject of
data: ATCC cell lines; Mus musculus

Sample size:
n=3 for all experiments, to assess variation in experimental approach(es) and
determine statistical significance; In vitro studies were replicated with two
different cell lines (MCF10A vs MCF10AT, T47D vs MCF7).

Trial
registration number:

Data
access

All data
files are openly available as part of this figshare
metadata record. A list of file names and the manuscript elements they
underlie is also available in the Excel spreadsheet ‘Grible_et_al_underlying_data_list.xlsx’.

All relevant
scripts can be found on GihHub at: https://github.com/AmyOlex/hPRLrI_TCGA.

Corresponding author(s) for this study

Charles
V. Clevenger, 1101 E. Marshall St, Sanger 4-006A, Richmond, VA 23298-0662, Phone:
804-828-0183, Fax: [phone].

Ethics

Virginia
Commonwealth University Institutional Animal Care and Use Committee (IACUC)
together with the Division of Animal Resources (DAR)