Baseline self-reported symptom scores, RNase L genotype, and XMRV status, for patients in the Rituximab and Placebo groups.

a: p-values from Student's t-test.
b: baseline self-reported symptom scores, generated as the mean (range) of relevant symptoms, as explained in Materials and Methods (scale 1–10; 1: no symptom, 5: moderate symptom, 10: very severe symptom, see Figure S1).
c: using Taqman SNP Genotyping (Applied Biosystems, assay c_935391_1).
d: including four Taqman qPCR and four nested PCR setups (see Table S1).
e: performed for nine patients using freshly drawn blood samples. Coculture of patient PBMNC with LNCap prostate cancer cells, and subsequent PCR, as described in Text S1.