Acyl-ACP thioesterase from Lemna paucicostata in complex with a spirolactam

Acyl-ACP thioesterase from Lemna paucicostata in complex with a spirolactam Descriptor: (5~{S})-9-[[2,6-bis(fluoranyl)phenyl]methyl]-3-(3-methylthiophen-2-yl)-1-oxa-2,9-diazaspiro[4.5]dec-2-en-10-one, Acyl-acp thioesterase Authors: Freigang, J. Deposit date: 2023-10-10 Release date: 2024-02-21 Last modified: 2025-04-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery and optimization of spirocyclic lactams that inhibit acyl-ACP thioesterase. Pest Manag Sci, 81, 2025本数据集为来自少根紫萍（Lemna paucicostata）的酰基-ACP硫酯酶（Acyl-ACP thioesterase）与螺内酰胺（spirolactam）的复合物。配体描述：(5S)-9-[[2,6-二氟苯基]甲基]-3-(3-甲基噻吩-2-基)-1-氧杂-2,9-二氮杂螺[4.5]癸-2-烯-10-酮。作者：Freigang, J.，存储日期：2023-10-10，发布日期：2024-02-21，最后修改日期：2025-04-16，实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率为2.3埃（Å）。引用文献：《抑制酰基-ACP硫酯酶的螺环内酰胺类化合物的发现与优化》，《害虫管理科学（Pest Manag Sci）》，2025年，第81卷。