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DNA methylation of colorectal cancer stem cells

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE123367
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Colorectal cancer stem cells (CR-CSCs) are implicated in tumor development, metastasis, and therapy resistance, however little is known about their epigenetic features. Here we describe the DNA methylation profiles of eight CR-CSC lines and their distinctive patterns, which are maintained following in vivo passages in immune-compromised mice. DNA was bisulfite-converted using the EZDNA Methylation-Gold Kit (Zymo Research) and analysed using the Infinium HumanMethylationEPIC BeadChip (Illumina) following manufacturer's instructions.
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2020-01-18
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