Replication dataset for "A comprehensive review and benchmark of differential analysis tools for Hi-C data"

colon37 Hi-C datasets. 5 matrices corresponding to technical replicates, all given at three different resolutions (200 kb, 500kb, 1Mb) and for three different chromosomes (1, 7, 21). Original sequencing data are ENCODE data from a Hi-C experiment performed on a human colon sample (experiment accession: ENCSR295BDK), that include five technical replicates (sequencing runs). To obtain Hi-C matrices, raw sequencing reads of each technical replicate were processed using the nf-core/hic pipeline v1.2.2 on the assembly version GRCh38 of the human genome. ctcf 6 matrices corresponding to biological replicates at 100 kb resolution. Raw interaction counts of the six Hi-C matrices were directly downloaded from the GEO platform uwing the accession ID GSE168251 from NCBI. File list: GSM5133388_120min_no_a_rep1.cool.gz SM5133389_120min_no_a_rep2.cool.gz GSM5133390_120min_no_a_rep3.cool.gz GSM5133391_120min_with_a_rep1.cool.gz GSM5133392_120min_with_a_rep2.cool.gz GSM5133393_120min_with_a_rep3.cool.gz . Matrices in cool format were exported using the HiC-Pro text format by chromosome at 100 kb resolution.