HIV-1 reverse transcriptase/rilpivirine with bound fragment 5-(trifluoromethyl)pyridin-2-ol at W24 site

HIV-1 reverse transcriptase/rilpivirine with bound fragment 5-(trifluoromethyl)pyridin-2-ol at W24 site Descriptor: 1,2-ETHANEDIOL, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, 5-(trifluoromethyl)pyridin-2-one, ... Authors: Chopra, A, Ruiz, F.X, Bauman, J.D, Arnold, E. Deposit date: 2022-08-02 Release date: 2023-05-31 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening. J.Med.Chem., 66, 2023HIV-1逆转录酶/利匹韦林结合于W24位点的片段5-(三氟甲基)吡啶-2-醇复合物。描述符：1,2-乙二醇、4-{[4-({4-[(E)-2-氰乙烯基]-2,6-二甲基苯基}氨基)嘧啶-2-基]氨基}苯甲腈、5-(三氟甲基)吡啶-2-酮…… 作者：Chopra, A、Ruiz, F.X、Bauman, J.D、Arnold, E。存档日期：2022-08-02；发布日期：2023-05-31；最后修改日期：2023-10-25。实验方法：X射线衍射（2.1 Å）。引用文献：《Halo文库：一种基于晶体学片段筛选快速鉴定蛋白质配体结合位点的工具》，《药物化学杂志》，66卷，2023年