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Enantioselective and regiodivergent skeletal transformations of 1,2,3-thiadiazoles to alkylidene dihydrothiophenes

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NIAID Data Ecosystem2026-05-02 收录
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http://datadryad.org/dataset/doi%253A10.5061%252Fdryad.sxksn03dz
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By leveraging the Rh-catalyzed asymmetric skeletal editing of 1,2,3-thiadiazoles, we successfully achieve the ligand-controlled enantioselective and regiodivergent synthesis of structurally diverse 2- and 3-alkylidene 2,3-dihydrothiophenes. Late-stage structural editing of complex natural and drug molecules is also enabled.
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2025-07-29
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