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A therapeutically targetable NOTCH1-SIRT1-KAT7 axis in T-ALL

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP376118
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资源简介:
C57BL6 mice harboring Sirt1 conditional knockout NOTCH1-DE-induced leukemias were treated with vehicle (control) or tamoxifen to induce isogenic deletion of Sirt1. Here we report the H4K12ac ChIP-seq epigenetic profile of leukemic blasts obtained from the spleen from control- or tamoxifen-treated leukemic mice. Overall design: Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for histone modification H4K12ac in mice
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2023-03-16
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