Nickel-Catalyzed Three-Component Domino Reactions of Aryl Grignard Reagents, Alkynes, and Aryl Halides Producing Tetrasubstituted Alkenes
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https://figshare.com/articles/dataset/Nickel_Catalyzed_Three_Component_Domino_Reactions_of_Aryl_Grignard_Reagents_Alkynes_and_Aryl_Halides_Producing_Tetrasubstituted_Alkenes/2187376
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Three-component reaction of aryl Grignard reagents, alkynes, and aryl halides in the presence of 1 mol % of NiCl2 proceeded sequentially through carbomagnesiation of the alkyne followed by cross-coupling of the resulting alkenyl Grignard reagent with aryl halide to give tetrasubstituted alkenes in high yields.
创建时间:
2016-02-14



