Asymmetric Bromolactonization Using Amino-thiocarbamate Catalyst
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https://figshare.com/articles/dataset/Asymmetric_Bromolactonization_Using_Amino_thiocarbamate_Catalyst/2714116
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资源简介：
A novel amino-thiocarbamate-catalyzed bromolactonization of unsaturated carboxylic acids has been developed. The scope of the reaction is evidenced by 22 examples of γ-lactones with up to 99% yield and 93% ee. The protocol was applied in the enantioselective synthesis of the key intermediates of VLA-4 antagonists.
创建时间：
2010-11-10
