OPA1 mutations associated with dominant optic atrophy affect mitochondrial fusion and cell death in a domain-specific manner
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP564580
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资源简介：
Our study uncovered the role of OPA1 BSE domain in modulation of mitochondrial dynamics and cell death, and characterized the related signaling pathways, hereby providing the insight into the understanding of the domain-specific effect of OPA1 on mitochondrial morphology and function. Overall design: RNA-seq profiling of wild type, OPA1, or OPA1 mutant(V560F,V465F) overexpressed in OPA1 knockdown cells in N2a cells
创建时间：
2025-04-29
