Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 5000 ms

Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 5000 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION, ... Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024

丝氨酸-β-内酰胺酶（serine-beta-lactamase）CTX-M-14在硼酸时间分辨活性位点结合及后续甘油-硼酸酯形成后的结构（时长5000 ms）；描述符：硼酸根离子（BORATE ION）、β-内酰胺酶（Beta-lactamase）、硫酸根离子（SULFATE ION）等。
作者：Prester, A、Perbandt, M、Galchenkova, M、Oberthuer, D、Yefanov, O、Hinrichs, W、Rohde, H、Betzel, C.
提交日期：2023-06-11；发布日期：2024-06-26；最后修改日期：2024-10-23
实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.5 Å）
引用文献：《CTX-M-14型β-内酰胺酶活性位点丝氨酸结合硼酸及后续1,2-二醇酯化反应的时间分辨晶体学研究》，《通讯化学》（Commun Chem），第7卷，2024年