Crystal Structure of Enterovirus 68 3C Protease with AG7404 at 1.97 Angstroms
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Crystal Structure of Enterovirus 68 3C Protease with AG7404 at 1.97 Angstroms Descriptor: Peptidase C3, SODIUM ION, ethyl (4R)-4-({(2S)-2-[3-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-2-oxopyridin-1(2H)-yl]pent-4-ynoyl}amino)-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate Authors: Azzolino, V.N, Shaqra, A.M, Schiffer, C.A. Deposit date: 2024-02-22 Release date: 2025-01-15 Last modified: 2025-02-05 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Structural Analysis of Inhibitor Binding to Enterovirus-D68 3C Protease. Viruses, 17, 2025
分辨率1.97埃的肠道病毒68型3C蛋白酶与AG7404共晶晶体结构
描述符:肽酶C3(Peptidase C3)、钠离子、(4R)-4-({(2S)-2-[3-{[(5-甲基-1,2-恶唑-3-基)羰基]氨基}-2-氧代吡啶-1(2H)-基]戊-4-炔酰基}氨基)-5-[(3S)-2-氧代吡咯烷-3-基]戊酸乙酯(ethyl (4R)-4-({(2S)-2-[3-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-2-oxopyridin-1(2H)-yl]pent-4-ynoyl}amino)-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate)
作者:Azzolino, V.N、Shaqra, A.M、Schiffer, C.A.
沉积日期:2024-02-22
发布日期:2025-01-15
最后修改日期:2025-02-05
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.97 Å
引用文献:《肠道病毒-D68型3C蛋白酶抑制剂结合的结构分析》,Viruses,2025年,第17卷
创建时间:
2024-02-22



