Gene expression analysis of male and female bone endothelial cells from 12 weeks old mice

Bone endothelial cells (ECs) were purified from male and female mice of 12 weeks old. RNA sequencing was performed to understand sex- dependent gene expression pattern in bone ECs during development and ageing to understand blood vesssel role in sex differences observed in bones. Further comparison of young and old mice would beneficial in understanding sex specific ageing mechanism. Overall design: Bone endothelial cells (ECs) were purified from male and female mice of 12 weeks old.