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Ubiquitin proteasome expression in Mulitple Myeloma cell lines

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE78884
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The ubiquitin proteasome system plays an important role in the pathophysiology of Multiple Myeloma, highlighted by the unique success of proteasome inhibitors in this malignancy. Using topic-defined microarrays we have looked at expression of ubiquitin proteasome system genes in 2 multiple myeloma cell lines and normal bone marrow samples. Normal bone marrow samples from 5 healthy donors and 2 multiple myeloma cell lines, OPM-2 (4 replicates) and U266 (3 replicates), were included in the study.
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2017-01-30
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