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Melatonin decreases extremely high glucose induced mesothelial cell injury

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE179519
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From initial RNAseq analysis, we found that a significant number of genes associated with inflammatory responses and related to mitochondrial structure and function were altered by high-glucose, while these changes were attenuated by melatonin treatment. Mesothelial cells were treated with normal or 236mM glucose in the presence or absence of 200mM melatonin and cells were collected after 6 and 12 hours.
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2023-07-03
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