Phosphine-Catalyzed Highly Enantioselective [3 + 3] Cycloaddition of Morita–Baylis–Hillman Carbonates with C,N-Cyclic Azomethine Imines
收藏NIAID Data Ecosystem2026-03-08 收录
下载链接：
https://figshare.com/articles/dataset/Phosphine_Catalyzed_Highly_Enantioselective_3_3_Cycloaddition_of_Morita_Baylis_Hillman_Carbonates_with_C_N_Cyclic_Azomethine_Imines/2178724
下载链接
链接失效反馈官方服务：
资源简介：
The first phosphine-catalyzed highly
enantioselective [3 + 3] cycloaddition
of Morita–Baylis–Hillman carbonates with C,N-cyclic
azomethine imines is described. Using a spirocyclic chiral phosphine
as the catalyst, a novel class of pharmaceutically interesting 4,6,7,11b-tetrahydro-1H-pyridazino[6,1-a]iso-quinoline
derivatives were obtained in high yields with good to excellent diastereoselectivities
and extremely excellent enantioselectivities (98–>99% ee).
创建时间：
2016-02-13
