Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the type 2 blood group A-tetrasaccharide (E558A X01 mutant)
收藏Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the type 2 blood group A-tetrasaccharide (E558A X01 mutant) Descriptor: 1,2-ETHANEDIOL, GLYCOSIDE HYDROLASE, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Kwan, D.H, Constantinescu, I, Chapanian, R, Higgins, M.A, Samain, E, Boraston, A.B, Kizhakkedathu, J.N, Withers, S.G. Deposit date: 2014-11-11 Release date: 2014-11-26 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Towards Efficient Enzymes for the Generation of Universal Blood Through Structure-Guided Directed Evolution. J.Am.Chem.Soc., 137, 2015
家族98糖苷水解酶催化模块（Sp3GH98）与2型血型A四糖（E558A X01突变体）结合的晶体结构。描述项：1,2-乙二醇、糖苷水解酶、α-L-吡喃岩藻糖-(1→2)-[2-乙酰氨基-2-脱氧-α-D-吡喃半乳糖-(1→3)]β-D-吡喃半乳糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖。作者：Kwan, D.H、Constantinescu, I、Chapanian, R、Higgins, M.A、Samain, E、Boraston, A.B、Kizhakkedathu, J.N、Withers, S.G。保藏日期：2014-11-11；发布日期：2014-11-26；最后修订日期：2023-12-20。实验方法：X射线衍射（分辨率1.98埃）。引用文献：《通过结构指导定向进化开发制备通用血型的高效酶》，《美国化学会志》，137卷，2015年
创建时间：
2014-11-11
