Polyanionic Carboxyethyl Peptide Nucleic Acids (ce-PNAs): Synthesis and DNA Binding
收藏Figshare2016-01-15 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Polyanionic_Carboxyethyl_Peptide_Nucleic_Acids_ce_PNAs_Synthesis_and_DNA_Binding/1577196
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资源简介：
New polyanionic modifications of polyamide nucleic acid mimics were obtained. Thymine decamers were synthesized from respective chiral α- and γ-monomers, and their enantiomeric purity was assessed. Here, we present the decamer synthesis, purification and characterization by MALDI-TOF mass spectrometry and an investigation of the hybridization properties of the decamers. We show that the modified γ-S-carboxyethyl-T10 PNA forms a stable triplex with polyadenine DNA.
创建时间：
2016-01-15
