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Bone marrow RNA sequencing profiles from AML patients and healthy donors

NIAID Data Ecosystem2026-05-10 收录

急性髓系白血病细胞异质性

AML转录组分析

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP667429 数据链接链接失效反馈

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资源简介：

RNA sequencing data were generated from bone marrow samples of acute myeloid leukemia (AML) patients and healthy donors to characterize cellular heterogeneity in AML.

应用场景：

创建时间：

2026-03-01

白血病干细胞标志物

AML转录组分析

To comprehensibly understand the genes and pathways associated with TMIGD2 expression in CD34-expressing leukemia cells, RNA-seq was conducted on FACS-purified CD34+TMIGD2+ and CD34+TMIGD2- subfractio

NIAID Data Ecosystem60

Gene expression in primary AML patients

AML转录组分析

治疗靶点发现

Cancer cell type-selective addiction of transcription-chromatin regulatory program provides opportunities for therapeutic interventions. Here, we uncovered an IRF8-MEF2D transcription factor (TF) regu

NIAID Data Ecosystem30

RNA-seq of AML cells with MPI KO and FLT3 tyrosine kinase inhibition. RNA-seq of AML cells with MPI KO and FLT3 tyrosine kinase inhibition

AML转录组分析

FLT3抑制剂与MPI敲除响应

Molm13 AML cell line both control and MPI KO, treated with AC220 (quizartinib) and mannose at 24 and 72 hours after drug treatment. 2 reads and 2 repeats for each condition, 2 timepoints, 48 total fil

NIAID Data Ecosystem10

RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14. Homo sapiens

AML转录组分析

METTL14敲低效应

To dissect the mechanism underlying the oncogenic function of METTL14 in AML, we performed deep sequencing for mRNA isolated from MM6 and NB4 cells with and without knockdown of METTL14 Overall design

NIAID Data Ecosystem30

Combinatorial genetics reveals the DOCK1-RAC2 axis as a specific target for the treatment of NPM1;Cohesin mutated AML

AML转录组分析

精准肿瘤学靶点发现

Acute myeloid leukemia (AML) is driven by mutations that occur in numerous combinations. A better understanding of how mutations interact with one another to cause disease is critical to developing ta

NIAID Data Ecosystem20

Bone marrow RNA sequencing profiles from AML patients and healthy donors

资源简介：

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