SPR binding parameters for HER2 constructs binding to the DARPin G3 and trastuzumab.
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Note 1: The values given are the average values for three separate measurements and the uncertainties represent one standard deviation.aNote 2: About 30-fold higher affinities are obtained when avoiding random amine coupling of this very small DARPin [9,36], (Nagy-Davidescu and Plückthun, unpublished).
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2015-12-02
