Gene expression analysis of fetal liver pro-B cells upon deletion of Early B-cell Factor 1 (Ebf1)

ChEBI2010-07-29 更新2026-07-21 收录

B细胞发育

转录因子功能基因组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-21454 数据链接链接失效反馈

官方服务：

资源简介：

Gene expression analysis of fetal liver pro-B cells upon deletion of Early B-cell Factor 1 (Ebf1)

创建时间：

2010-07-29

Phospholipase Cγ pathway-dependent mTOR signaling controls IL-7-mediated early B cell development. Mus musculus

B细胞发育

信号转导分析

We examined the global gene expression profile of PLCγ1/PLCγ2 double-deficient CLPsand B cell progenitors by RNA-seq analysis. Overall design: CLPs (Lin-IL-7R+) and B cell progenitors (B220+IgM-IL-7R+

NIAID Data Ecosystem100

A missense mutation in AIOLOS causes B cell deficiency by interfering with IKAROS. A missense mutation in AIOLOS causes B cell deficiency by interfering with IKAROS

B细胞发育

转录因子功能干扰

A missense mutation (G158R) in Ikzf3 gene resulted in defective generation of B cells in mice. Pre-B cells were profoundly decreased in homozygous mutant mice. Heterozygous mutant mice showed milder B

NIAID Data Ecosystem60

Polypyrimidine tract binding proteins are essential for B cell development. Polypyrimidine tract binding proteins are essential for B cell development

B细胞发育

转录调控

During B cell development, recombination of immunoglobulin loci is tightly coordinated with the cell cycle to avoid unwanted rearrangements of other genomic locations. Several factors have been identi

NIAID Data Ecosystem50

Gene expression profiles of FoxO4 overexpressing TH1 cells.

T细胞分化

转录因子功能基因组学

To assess the function of FoxO4 in processes of TH1 differentiation, we have performed a whole genome microarray assay to discover the significant changed genes in normal and FoxO4 overexpressing TH1

NIAID Data Ecosystem70

The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement. The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement

B细胞发育

剪接体功能

The spliceosome is a large ribonucleoprotein complex responsible for pre-mRNA splicing and genome stability maintenance. Disruption of the spliceosome activity may lead to developmental disorders and

NIAID Data Ecosystem60

Gene expression analysis of fetal liver pro-B cells upon deletion of Early B-cell Factor 1 (Ebf1)

资源简介：

相关数据集