Large cell neuroendocrine carcinoma - Male, 72 - Tissue image [12060630017636061]

This is the histopathological image of BRONCHUS AND LUNG tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 72Clinical description: Right lower lobe with tumor 13 cm in diameterGender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: EPITHELIAL NEOPLASMS, NOSDiagnosis: Large cell neuroendocrine carcinomaResult of the histopathological examination: Large cell neuroendocrine carcinoma, G3, pT4
Immunophenotype: CD56 (+) / TTF1 (-) / p40 (-)
Ki67 Proliferation Index: 75%.
Large cells (~3x size of small cell carcinoma) with abundant cytoplasm, variably coarse chromatin, nuclear pleomorphism, prominent nucleoli
The tumor was largely necroticSample:Material: FFPECollecting method: Surgical specimenTopography: RESPIRATORY SYSTEM AND INTRATORACIC ORGANSOrgan: BRONCHUS AND LUNGTissue: Lower lobe, lungType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk