Synthesis of Polysubstituted 3‑Aminothiophenes from Thioamides and Allenes via Tandem Thio-Michael Addition/Oxidative Annulation and 1,2-Sulfur Migration
收藏NIAID Data Ecosystem2026-03-10 收录
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https://figshare.com/articles/dataset/Synthesis_of_Polysubstituted_3_Aminothiophenes_from_Thioamides_and_Allenes_via_Tandem_Thio-Michael_Addition_Oxidative_Annulation_and_1_2-Sulfur_Migration/5782245
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资源简介：
A facile synthetic
method for the construction of 3-aminothiophenes
from readily available thioamides and alllenes in the presence of
a TBAI/TBHP catalyst system was developed. This protocol represents
an efficient and straightforward way to access highly functionalized
thiophenes in moderate to excellent yields under mild conditions,
via a tandem thio-Michael addition, oxidative annulation, and 1,2-sulfur
migration pathway.
创建时间：
2018-01-11
