Plating efficiency of wild type and mutant diploids before and after the creation of multiple double-strand breaks by HO endonucleasea.

aMedian plating efficiencies on non-selective medium±the 95% confidence interval were determined by plating a known number of cells before and after induction of the expression of HO endonuclease for four hours from a minimum of five independent trials using pre-senescent cultures.bTranslocation substrates were as described in the Materials and Methods.