Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with ASAP-0038553-001 (A71EV2A-x5317)

Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with ASAP-0038553-001 (A71EV2A-x5317) Descriptor: (3S)-1-[(1S)-2-(methylamino)-1-(3-methylphenyl)-2-oxoethyl]-5-oxopyrrolidine-3-carboxamide, DIMETHYL SULFOXIDE, Protease 2A, ... Authors: Lithgo, R.M, Fairhead, M, Koekemoer, L, Balcomb, B.H, Capkin, E, Chandran, A.V, Golding, M, Godoy, A.S, Aschenbrenner, J.C, Marples, P.G, Ni, X, Thompson, W, Tomlinson, C.W.E, Wild, C, Winokan, M, Xavier, M.-A.E, Kenton, N, Tucker, J, DiPoto, M, Lee, A, Fearon, D, von Delft, F. Deposit date: 2025-03-12 Release date: 2025-04-02 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (1.31 Å) Cite: Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre To Be Published

本数据集为柯萨奇病毒A16（Coxsackievirus A16）G-10株2A蛋白酶（Protease 2A）与ASAP AViDD中心来源抑制剂的群组沉积数据——具体为柯萨奇病毒A16（Coxsackievirus A16）G-10株2A蛋白酶与ASAP-0038553-001（A71EV2A-x5317）复合物的晶体结构。
结构描述符：(3S)-1-[(1S)-2-(甲氨基)-1-(3-甲基苯基)-2-氧代乙基]-5-氧代吡咯烷-3-甲酰胺、二甲基亚砜（DIMETHYL SULFOXIDE）、2A蛋白酶（Protease 2A）……
作者：Lithgo, R.M.、Fairhead, M.、Koekemoer, L.、Balcomb, B.H.、Capkin, E.、Chandran, A.V.、Golding, M.、Godoy, A.S.、Aschenbrenner, J.C.、Marples, P.G.、Ni, X.、Thompson, W.、Tomlinson, C.W.E.、Wild, C.、Winokan, M.、Xavier, M.-A.E.、Kenton, N.、Tucker, J.、DiPoto, M.、Lee, A.、Fearon, D.、von Delft, F.
沉积日期：2025-03-12；发布日期：2025-04-02；最后修改日期：2025-04-09
实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.31 Å）
引用信息：《柯萨奇病毒A16（G-10）2A蛋白酶与ASAP AViDD中心来源抑制剂的群组沉积数据》，待发表。