A: Diffusion and advection layers identified in the fibrin cap for thrombin and Fab IgG.

Diffusion prevails near the thrombus surface and depends on molecular size. Smaller than Fab IgG complexes thrombin molecules have higher mobility resulting in thicker diffusion layer. Diffusion layer profiles for thrombin and Fab IgG for low () and high () fibrin cap permeabilities are shown. Flow Reynolds number , , . B: Force acting on a thrombus surface as a function of the permeability of the fibrin cap for different radii values of the core, , and the thrombus, . For each permeability value, the force is non-dimensionalized by the force acting on a nonpermeable thrombus of the same size.