Butyricicoccus sp. BIOML-A1 tryptophanase complex with (3S) ALG-05

Butyricicoccus sp. BIOML-A1 tryptophanase complex with (3S) ALG-05 Descriptor: (E)-3-[(3S)-3-chloro-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-alanine, Tryptophanase Authors: Graboski, A.L, Redinbo, M.R. Deposit date: 2023-04-21 Release date: 2023-08-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate. Cell Chem Biol, 30, 2023丁酸球菌属（Butyricicoccus sp.）菌株BIOML-A1的色氨酸酶复合物结合(3S)-ALG-05 描述符：(E)-3-[(3S)-3-氯-2-氧代-2,3-二氢-1H-吲哚-3-基]-N-({3-羟基-2-甲基-5-[(膦酰氧基)甲基]吡啶-4-基}亚甲基)-L-丙氨酸，色氨酸酶（Tryptophanase） 作者：Graboski, A.L.、Redinbo, M.R. 提交日期：2023-04-21 发布日期：2023-08-23 最后修改日期：2023-11-29 实验方法：X射线衍射（分辨率2.07埃） 引用文献：基于机制的肠道微生物色氨酸酶抑制可降低血清吲哚硫酸酯水平，Cell Chem Biol, 30, 2023