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AfBPP of Navtemadlin probes in SJSA-1 cells

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NIAID Data Ecosystem2026-05-02 收录
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https://www.omicsdi.org/dataset/pride/PXD058033
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Navtemadlin is a potent small moeclule inhibitor of the p53-MDM2 protein-protein interaction, that is being tested in Phase II/III clinical trials for the treatment of cancer. The selectivity of this molecule is poorly understood. So we synthesised and validated two photoactivatable clickable probes of Navtemadlin. This data shows the proteins enriched upon treatment of SJSA-1 cells with these probes.
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2025-04-28
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