AVM

AVM is a comprehensive and manually curated compilation of virus mutations associated with aerosol-transmitted human diseases. The data on mutations and related data have been extracted from published literature and preprints, including drug/antibodies/vaccines, immune escape, clinical information, human diseases and the effects of mutations on virus function. AVM offers a list of mutations that have been experimentally verified to be associated with transmissibility and pathogenicity of the virus. The AVM resource provides a user friendly and searchable interface to query and understand the mutation and their functional annotations in detail. This resource can help researchers further understand the mechanism of viral diseases.AVM是一套经人工手动整理的综合性数据集，收录了与气溶胶传播人类疾病相关的病毒突变。数据集内的突变及关联数据均提取自已发表文献与预印本，涵盖药物、抗体、疫苗、免疫逃逸、临床信息、人类疾病，以及突变对病毒功能的影响等相关内容。AVM提供了经实验验证、与病毒传播性和致病性相关的突变列表。该数据集资源配备了友好易用且支持检索的交互界面，可用于详细查询并深入了解各类突变及其功能注释信息。该资源可助力研究人员进一步解析病毒性疾病的致病机制。

搜集汇总

背景与挑战

背景概述

AVM是一个手动整理的综合数据库，专注于气溶胶传播病毒突变及其与人类疾病的关联，包含9种病毒、42401个突变条目和407种相关药物。它提供实验验证的突变数据，涉及传播性和致病性，并支持用户通过友好界面查询详细功能注释，以帮助研究者深入理解病毒疾病机制。