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Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41: Crystals cryoprotected with phosphatidic acid (08:0 PA)

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41: Crystals cryoprotected with phosphatidic acid (08:0 PA) Descriptor: 4E10 Fab heavy chain, 4E10 Fab light chain, FRAGMENT OF HIV GLYCOPROTEIN (GP41) including the MPER region 671-683, ... Authors: Irimia, A, Stanfield, R.L, Wilson, I.A. Deposit date: 2014-12-15 Release date: 2016-02-03 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10. Immunity, 44, 2016

人类4E10抗原结合片段(Fab)与HIV-1 gp41肽表位结合的晶体结构:晶体采用磷脂酸(08:0 PA)进行冷冻保护处理 描述项:4E10 Fab重链、4E10 Fab轻链、包含膜近端外部区域(MPER, Membrane-Proximal External Region)671-683位的HIV糖蛋白(GP41)片段…… 作者:Irimia A、Stanfield R.L.、Wilson I.A. 提交日期:2014-12-15 发布日期:2016-02-03 最后更新:2024-11-13 实验方法:X射线衍射(1.47 Å) 引用文献:《晶体学鉴定脂质为HIV广谱中和抗体4E10表位的组成部分》,《免疫(Immunity)》,第44卷,2016年
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2014-12-15
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