CBP bromodomain complexed with YF2-23
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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https://pdbj.org/mine/summary/7juo
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资源简介：
CBP bromodomain complexed with YF2-23 Descriptor: CREB-binding protein, N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-(1-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-3-yl)-1H-indol-4-yl}ethanesulfonamide Authors: Ratia, K.M, Xiong, R, Principe, D, Li, Y, Huang, F, Rana, A, Thatcher, G. Deposit date: 2020-08-20 Release date: 2021-09-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.2 Å) Cite: XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer. Proc.Natl.Acad.Sci.USA, 119, 2022
创建时间：
2020-08-20
